Comprehensive evaluation on genuineness of plant medicinal materials based on historical inheritances and scientific connotations
Genuine medicinal materials are the essence of traditional Chinese medicine(TCM)culture and treasure of Chinese national culture,and its genuine evaluation is not only related to the healthy and scientific development of TCM industry,but also the key to promote the modernization and internationalization of TCM.In recent years,blind introduction of species has caused problems such as disorder in the germplasm resources of genuine medicinal materials in genuine producing areas.Therefore,this paper reviews the development history of genuine medicinal materials from perspective of historiography,which basic context is that the ancient people gradually realized the effects of origin,habitat,form,harvesting season and location,processing methods,storage methods,and other factors on medicinal effects with the drug effect as the center.Then the scientific connotation of genuineness in genuine medicinal materials was analyzed from the aspects of"(herbal)plant taxonomy","genetics","ecology","cultivation","processing",and"pharmacology".On this basis,a system was proposed for evaluating the genuineness of a certain genotype(or variety)of a certain type of herb.The initial stage of this evaluation system is to ascertain the"genuine genotype populations"of a specific type of genuine medicinal materials,based on the findings of mainstream herbological,genetic,botanical,pharmacological,chemical and metabolomic analyses.This is subsequently employed as a foundation for a more precise evaluation of the veracity of a specific genotype(or variety)of the same category of medicinal herb in the future.This system provides a theoretical foundation and technical reference for the identification of genuineness of plant medicinal materials,standardization of cultivation,quality estimation,genuineness evaluation,trading and circulation,comprehensive protection and sustainable utilization.
Chinese medicinal materialsgenuine medicinal materialsplant medicinal materialsgenotypegenuinenesscomprehensive evaluation