Research progress on anti-melanoma metastasis of traditional Chinese medicine and its active ingredients
Melanoma is one of the highly metastatic tumors.The main metastatic organs are lung,lymph nodes,brain and so on.The metastasis of melanoma is closely related to epithelial-mesenchymal transition(EMT),metabolic reprogramming and immune microenvironment.EMT makes melanoma cells more invasive,accompanied by metabolic reprogramming,providing energy support for cells,promoting immune escape,and promoting tumor development and metastasis.Traditional Chinese medicine plays a role in anti-melanoma metastasis by inhibiting EMT process,regulating metabolic reprogramming and remodeling immune microenvironment.This paper systematically reviews the metastasis process of melanoma and the research progress of traditional Chinese medicine against melanoma metastasis,and provides scientific basis and theoretical basis for the study of traditional Chinese medicine against melanoma.
traditional Chinese medicineactive ingredientsmelanoma metastasisepithelial-mesenchymal transitionmetabolic reprogrammingimmune microenvironment
NETL
NSTL
万方数据
