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针刺治疗功能性便秘的机制研究进展

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针刺治疗功能性便秘(FC)疗效确切,具有早期起效迅速、远期疗效稳定和整体性调节的特点.本文检索并总结近年来针刺治疗FC的相关文献,结果显示针刺能从促进肠道动力、调节肠道菌群、调节脑-肠轴、减轻肠道炎性反应、改善直肠低敏感性等多角度、多途径发挥作用.未来研究可深入挖掘针刺改善直肠低敏感性的机械传感机制、明确针刺调控的关键肠道菌属及代谢特征、探究不同作用机制间的网络关系,并阐明不同针刺治疗方案的效应差异机制,以期更好地优化临床治疗方案,提高针刺治疗FC的临床疗效.
Research progress on mechanism of acupuncture in treating functional constipation
Acupuncture treatment for functional constipation(FC)is characterized by precise efficacy,rapid on-set of action in the early stages,long-term stable effects,and overall regulation.This paper reviews recent literatures on acupuncture treatment for FC,indicating that acupuncture acts from multiple perspectives and pathways,including promoting intestinal motility,regulating intestinal microbiota,modulating the brain-gut axis,alleviating intestinal inflam-mation,and improving rectal hyposensitivity.Future research could delve into the mechanical sensation conduction mechanisms of acupuncture in improving rectal hyposensitivity,identify key intestinal microbiota genera and metabolic characteristics regulated by acupuncture,explore the network relationships among different mechanisms,and clarify the differential mechanisms of various acupuncture treatment protocols to optimize clinical therapy and enhance the clinical efficacy of acupuncture for FC.

Functional constipationAcupunctureMechanismReview

李艳秋、姚俊鹏、鄢香芸、杨婉卿、陈敏、唐太春、李瑛

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成都中医药大学针灸推拿学院,成都 610075

成都中医药大学附属医院,成都 610075

功能性便秘 针刺 机制 综述

国家自然科学基金项目国家自然科学基金项目四川省科技厅应用基础项目

82074554822746522021YJ0197

2024

针刺研究
中国中医研究院针灸研究所,中国针灸学会

针刺研究

CSTPCD北大核心
影响因子:1.656
ISSN:1000-0607
年,卷(期):2024.49(1)
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