Research progress on mechanisms of acupuncture and moxibustion underlying improvement of oxidative stress
Oxidative stress is associated with a variety of disease pathologies,it may lead to mitochondrial dys-function,damage of impaired DNA repairment,cell damage or apoptosis.Acupuncture and moxibustion therapy has been proved to have a role in reducing oxidative stress in organisms under pathological conditions.In the present pa-per,we collected literatures in both English and Chinese from domestic and foreign databases on the mechanisms of acupuncture and moxibustion underlying amelioration of oxidative stress over the past 5 years,and analyzed the link between acupuncture-moxibustion intervention and redox biology from four aspects:1)regulation of the production of reactive oxygen species(ROS),2)affecting antioxidant enzyme-related pathways to reduce ROS,3)repairing pro-teins,lipids and DNAs attacked by ROS,and 4)inhibiting downstream apoptosis or autophagy of ROS pathway.By summarizing and prospecting such antioxidant mechanisms,this paper may provide some basis and ideas for in-depth mechanism research on acupuncture and moxibustion to improve oxidative stress and related diseases.
国家科技期刊平台
NSTL
万方数据
