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针灸协同化疗实现增效的研究进展

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针灸在减轻化疗药物不良反应方面的应用已经得到国内外的广泛认可,而对于其协同化疗增加抗肿瘤疗效的效应及其机制则较少进行归纳总结.本文对近几年针灸联合化疗增效的临床及基础研究进行回顾,结果显示针灸可一定程度协同化疗抑瘤,并改善患者生存质量;其效应机制与针灸联合化疗药物可促进肿瘤细胞凋亡、改善肿瘤免疫及血管微环境、促进肿瘤局部化疗药富集等有关.本文为针灸作为提高化疗疗效的辅助疗法提供证据和研究思路.
Research progress of acupuncture and moxibustion for the enhanced synergism of chemotherapy
The application of acupuncture and moxibustion in alleviating the adverse effects of chemotherapy drugs has been widely recognized at home and abroad,but the studies have been rarely summarized for the enhanced anti-tumor effect and its mechanism of acupuncture and moxibustion to synergize the chemotherapy drugs.This paper reviewed the clinical and basic studies on the synergism of chemotherapy with acupuncture and moxibustion in recent years.It was found that chemotherapy synergized with acupuncture and moxibustion can suppress cancer to a certain extent and improve the quality of life in patients.The effect mechanism of acupuncture and moxibustion combined with chemotherapy drugs is related to promoting tumor cell apoptosis,improving the immune and vascular microenvironment,and advancing chemotherapy drug enrichment on the affected area.It provides the evidences and ideas for enhancing the effect of chemotherapy by delivering acupuncture and moxibustion as an adjuvant therapy.

Acupuncture and moxibustionTumorChemotherapySynergism

杨元祯、李姗姗、郭义、黄锦、王佳琦、冯怡婷、赵素红、赵文君、徐枝芳

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天津中医药大学实验针灸学研究中心,天津 301617

天津中医药大学中医学院,天津 301617

日本埼玉大学理工学研究科生命科学部,日本埼玉330-9301

天津中医药大学针灸推拿学院,天津 301617

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针灸 肿瘤 化疗 增效

国家自然科学基金重点项目天津市大学生创新创业训练计划

82030125202210063035

2024

针刺研究
中国中医研究院针灸研究所,中国针灸学会

针刺研究

CSTPCD北大核心
影响因子:1.656
ISSN:1000-0607
年,卷(期):2024.49(6)
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