Comparative study of different dosages of grain-sized moxibustion on uterine artery blood flow in patients with cold and dampness primary dysmenorrhea
Objective To observe the differences in the effects of different dosages of grain-sized moxibustion on uterine artery blood flow in patients with cold and dampness primary dysmenorrhea(PD).Methods A total of 60 patients with PD were randomly divided into 3 groups with 20 cases in each group.Acupoints Sanyinjiao(SP6),Diji(SP8)and Xuehai(SP10)were selected in all the 3 groups,and different dosages of grain-sized moxibustion were used(3 moxa cones,6 moxa cones,9 moxa cones)respectively.Treatment started 7 days before menstruation for 3 times,lasting for a total of 3 menstrual cycles.The values of uterine artery blood flow parameters including pulsatility index(PI),resistance index(RI),and systolic/diastolic ratio(S/D)were recorded before and after treatment.The visual analog scale(VAS)score and cox menstrual symptom scale(CMSS)score(including severity[CMSS-S]and time of duration[CMSS-T])were evaluated before treatment,at the end of each menstrual cycle,and one menstrual cycle after treatment.Results The values of uterine artery blood flow parameters(PI,RI,S/D)after treatment in the 9 moxa cones group were lower than those before treatment,as well as lower than those in the 3 and 6 moxa cones groups after treatment(P<0.05).The VAS scores of the 3 moxa cones group were lower than those before treatment in the first and second cycle(P<0.05).The VAS scores of the 6 and 9 moxa cones groups were lower than those before treatment at each observation point(P<0.05),and were lower than those of the 3 moxa cones group in the third cycle of treatment and follow-up period(P<0.05).And the VAS score of the 9 moxa cones group was lower than that of the 6 moxa cones group during the follow-up period(P<0.05).Compared with the scores before treatment,the CMSS-T scores at each observation point after treatment were lower in the 9 moxa cones group(P<0.05);the CMSS-T scores in the second and third cycle after treatment,and follow-up period were lower in the 6 moxa cones group(P<0.05),with the CMSS-S scores in the second and third cycle after treatment,and follow-up period lower in the 6 and 9 moxa cones groups(P<0.05).The CMSS-T and CMSS-S scores of the 6 and 9 moxa cones groups were lower than those of the 3 moxa cones group in the third cycle and follow-up period(P<0.05).The CMSS-T and CMSS-S scores of the 9 moxa cones group were lower than those of the 6 moxa cones group during the follow-up period(P<0.05).Conclusion Grain-Sized moxibustion has dose-effect relationship in the treatment of PD.Compared with 3 and 6 moxa cones groups,9 moxa cones group has advantages in improving uterine artery blood flow parameters and alleviating dysmenorrhea symptoms in PD patients.
Primary dysmenorrheaQuantities of moxibustionCold and dampnessUterine artery blood flow
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