Clinicopathological features and prognosis of immature teratoma:analysis of 30 cases
Objective To explore the clinicopathological features and prognosis of immature teratoma.Methods Thirty cases of immature teratoma admitted to Northwest Women's and Children's Hospital from March 2013 to March 2023 were retrospectively analyzed.Results The age of the 22 primary ovarian patients was 7-73 years old.The 8 non-primary ovarian patients were all found by physical examination during pregnancy.The mass was 5-30 cm in diameter,histological grades were as follows:G1 12 cases,G2 12 cases,G3 6 cases.Age,gender,maximum diameter of tumor,sites of disease,and FIGO stages were not correlated with the histological grades(P>0.05),while mixed germ cell tumors were correlated with the histological grades(P<0.05).Univariate analysis showed that gender,maximum tumor diameter,sites of onset,surgical method,FIGO stags,and histological grades were the prognostic factor of patients(P<0.05),while multivariate analysis showed that maximum tumor diameter was the independent prognostic factor of patients(P<0.001).Conclusion Immature teratomas have a poor prognosis,surgery combined with chemotherapy plays an important role in their treatment,and FIGO staging and histologic grading are important parameters affecting the prognosis.