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未成熟性畸胎瘤30例临床病理特征及预后分析

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目的 探讨未成熟性畸胎瘤的临床病理特征及预后.方法 收集西北妇女儿童医院2013-03-2023-03未成熟性畸胎瘤30例进行回顾性分析.结果22例卵巢原发患者年龄7~73岁,8例非卵巢原发患者均为孕期体检发现.肿物直径5~30 cm,组织学分级G1 12例、G2 12例、G3 6例.年龄、性别、肿物最大径、部位、FIGO分期与组织学分级无关(P>0.05),混合生殖细胞肿瘤与组织学分级有关(P<0.05).单因素分析显示性别、肿物最大径、部位、手术方式、FIGO分期、组织学分级是影响患者预后的因素(P<0.05),多因素分析显示肿物最大径是影响患者的独立预后因素(P<0.001).结论 未成熟性畸胎瘤预后差,手术联合化疗在其治疗中起重要作用,FIGO分期和组织学分级是影响预后的重要参数.
Clinicopathological features and prognosis of immature teratoma:analysis of 30 cases
Objective To explore the clinicopathological features and prognosis of immature teratoma.Methods Thirty cases of immature teratoma admitted to Northwest Women's and Children's Hospital from March 2013 to March 2023 were retrospectively analyzed.Results The age of the 22 primary ovarian patients was 7-73 years old.The 8 non-primary ovarian patients were all found by physical examination during pregnancy.The mass was 5-30 cm in diameter,histological grades were as follows:G1 12 cases,G2 12 cases,G3 6 cases.Age,gender,maximum diameter of tumor,sites of disease,and FIGO stages were not correlated with the histological grades(P>0.05),while mixed germ cell tumors were correlated with the histological grades(P<0.05).Univariate analysis showed that gender,maximum tumor diameter,sites of onset,surgical method,FIGO stags,and histological grades were the prognostic factor of patients(P<0.05),while multivariate analysis showed that maximum tumor diameter was the independent prognostic factor of patients(P<0.001).Conclusion Immature teratomas have a poor prognosis,surgery combined with chemotherapy plays an important role in their treatment,and FIGO staging and histologic grading are important parameters affecting the prognosis.

Immature teratomaGerm cell tumorHistological gradeClinicopathological parameters

欧达、王明娟

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西北妇女儿童医院病理科,西安 710061

未成熟性畸胎瘤 生殖细胞肿瘤 组织学分级 临床病理参数

2024

诊断病理学杂志
北京军区总医院

诊断病理学杂志

CSTPCD
影响因子:0.663
ISSN:1007-8096
年,卷(期):2024.31(1)
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