Application of PSC and WHO reporting system for pancreaticobiliary cytopathology in diagnosis of pancreatic masses
Objective To explore the application of Papanicolaou Society of Cytopathology(PSC)and World Health Organization(WHO)reporting system for pancreaticobiliary cytopathology in the diagnosis of pancreatic masses.Methods This paper reviewed 411 cases of pancreatic endoscopic ultrasound guided fine needle aspiration cytopathology(EUS-FNAC).According to the pancreaticobiliary cytology reporting system issued by PSC and WHO,the cytological and pathological reports were classified for diagnosis and compared with the result of histopathological examination.Results According to the PSC reporting system,18(4.4％)were diagnosed as grade 1;155 cases(37.7％)were diagnosed as grade Ⅱ;32 cases(7.8％)were diagnosed as grade Ⅲ;64 cases(15.6％)were diagnosed as grade Ⅳ(including 14 cases of ⅣA grade and 50 cases of ⅣB grade);51 cases(12.4％)were diagnosed as grade Ⅴ;91 cases(22.1％)were diagnosed as grade Ⅵ.According to the WHO reporting system,the classification of Ⅰ-Ⅲ lesions was consistent with the PSC classification;14 cases(3.4％)were diagnosed as grade Ⅳ;39 cases(9.4％)were diagnosed as grade V;51 cases(12.4％)were diagnosed as grade Ⅵ;102 cases(24.9％)were diagnosed as grade Ⅶ.Compared with the result of histopathological examination,the accuracy of FNAC in the diagnosis of pancreatic tumors was 95.7％(376/393),sensitivity was 96.5％(196/203),and specificity was 94.7％(180/190).There was no difference in the accuracy and specificity of tumor diagnosis between PSC and WHO.Conclusion PSC and WHO reporting system for pancreaticobiliary cytopathology can effectively communicate with clinical doctors.
Endoscopic ultrasound guided fine needle aspiration cytopathologyPSC reporting system for pancreaticobiliary cytopathologyWHO reporting system for pancreaticobiliary cytopathology
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