首页|腹膜播散性平滑肌瘤病6例临床病理分析

腹膜播散性平滑肌瘤病6例临床病理分析

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目的 通过分析临床病理特征,提高对腹膜播散性平滑肌瘤病(LPD)的认识,为临床诊治提供帮助.方法 本文回顾性分析本院术后病理确诊的6例LPD患者,结合文献复习其临床特征及病理组织学等特点.结果 患者均有子宫肌瘤切除既往史,且本次术后病理均符合腹膜播散性平滑肌瘤病.免疫组化结果:SMA、H-caldesmon均为阳性;ER和PR为弥漫阳性;Ki-67指数平均为4%(值域:1%~8%).结论 LPD的确诊需结合临床及病理特征,提示临床工作中应尽量减少因医源性因素导致LPD发生的可能,且对于术后病理亚型为富于细胞型的子宫平滑肌瘤应加强随访.
Peritoneal disseminated leiomyomatosis:a clinicopathological analysis of six cases
Objective Our study aimed to understand better leiomyomatosis peritonealis disseminate(LPD)by analyzing clinical and pathological features to assist in clinical diagnosis and treatment.Methods We reviewed six LPD cases at Beijing Chaoyang Hospital,Capital Medical University,and analyzed their clinical features,pathology,and immunohistochemistry.Results All patients had a history of uterine fibroid resection,and the postoperative pathology was consistent with peritoneal disseminated leiomyomatosis.Immunohistochemical result:SMA and H-caldesmon were positive;ER and PR were diffusely positive;The average Ki67 index was 4%(range:1%-8%).Conclusion The diagnosis of LPD needs to be based on history,intraoperative exploration,and postoperative pathological result.In our clinical work,iatrogenic spread due to myomectomy needs be minimized,and follow-up needs be strengthened for uterine leiomyoma with a cellular subtype.

Leiomyomatosis peritonealis disseminateLeiomyomaPeritoneal tumorUterine neoplasmsLeiomyomatosis

曾贝贝、金木兰、谢燕、陈红

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首都医科大学附属北京朝阳医院石景山院区病理科,北京 100043

腹膜播散性平滑肌瘤病 平滑肌瘤 腹膜肿瘤 子宫肿瘤 平滑肌瘤病

2024

诊断病理学杂志
北京军区总医院

诊断病理学杂志

CSTPCD
影响因子:0.663
ISSN:1007-8096
年,卷(期):2024.31(4)