Research and application of exosomes in the diagnosis and treatment of ischemic stroke
Ischemic stroke(IS)is the most common type of stroke that can lead to severe neurological dysfunction while effective diagnostic and therapeutic methods are currently limited.Exosomes are natural vesicles that can play a key role in intercellular communication by delivering proteins,lipids,and nucleic acids.Notably,IS could cause changes in the level and content of exosome,which can serve as a potential biomarker to assist the diagnosis and treatment of IS.This article reviews the potential diagnostic value of exosomes,discusses their repair effects,and explores the potential applica-tion as drug carriers in IS.We also provide a concise summary of the current clinical research status based on exosomes.