斑块内新生血管分级与颈动脉粥样硬化程度相关性的新进展
New progress on the relationship between the grade of intraplaque neovascularization and the degree of carotid atherosclerosis
范佳煜 1董亚男 1白竹 1陈盈 1王丽娟1
作者信息
- 1. 吉林大学第一医院神经内科和神经科学中心,吉林 长春 130021
- 折叠
摘要
颈动脉粥样硬化是导致缺血性事件发生的重要危险因素.颈动脉斑块负荷及颈动脉狭窄均与缺血性事件发生密切相关,此外,颈动脉斑块内成分也与缺血性事件发生息息相关.斑块内新生血管(intraplaque neo-vascularization,IPN)作为易损斑块的特征成分,通过多种机制参与颈动脉粥样斑块形成.本篇综述重点关注IPN分级与颈动脉粥样硬化程度的关系.
Abstract
Carotid atherosclerosis is an important risk factor leading to ischemic events.Carotid plaque load and ca-rotid artery stenosis are closely related to the occurrence of ischemic events.In addition,the composition of carotid artery plaques is also closely associated with the occurrence of ischemic events.Intraplaque neovascularization(IPN),as a char-acteristic component of vulnerable plaques,participates in the formation of carotid atherosclerotic plaques through a vari-ety of mechanisms.This review focuses on the relationship between IPN grading and the degrees of carotid atherosclerosis.
关键词
动脉粥样硬化/缺血性事件/斑块内新生血管/颈动脉狭窄Key words
Arteriosclerosis/Ischemic event/Intraplaque neovascularization/Carotid stenosis引用本文复制引用
基金项目
国家自然科学基金(82102066)
吉林省自然科学基金(YDZJ202201ZYTS139)
吉林省科技厅项目(20230508100RC)
吉林科技厅自然科学研究项目(20210101254JC)
出版年
2024
国家科技期刊平台
NSTL
维普
万方数据