Research advances in DNA methylation/demethylation in regulating ischemic stroke
Stroke is the leading cause of death and disability in China.Ischemic stroke(IS)is the dominantsubtype of stroke with a proportion more than 80%.Certainly,IS is a complex disease with a ge-neticpredisposition.DNA methylation/demethylation is a crucial epigenetic mechanism,which has been found to play an important role in the pathogenesis and recurrence of IS in recent years,indicating that DNA methylation/demethylation may be potential diagnostic biomarker and therapeutic targets for IS.The latest advances of DNA methylation/demethylation in IS is summarized as follows.
国家科技期刊平台
NSTL
万方数据
维普
