Objective To investigate the influencing factors for white matter hyperintensity(WMH)in middle-aged and elderly patients with hypertension,and to establish and verity a nomogram prediction model.Methods A total of 198 middle-aged and elderly patients with hypertension and WMH who were hospitalized in our hospital from January 2022 to April 2023 were enrolled.Related clinical data were analyzed,and related data were recorded.A binary logistic regression analysis was used to investigate the independent risk factors for WMH and establish a nomogram,and the re-ceiver operating characteristic(ROC)curve and the calibration curve were used to evaluate the diagnostic efficacy of the nomogram.Results Age,course of hypertension,cystatin C,homocysteine,red blood cell distribution width,and cognitive impairment were the independent influencing factors for WMH in the middle-aged and elderly patients with hypertension.The nomogram established showed good diagnostic efficacy(AUC=0.815,95%CI 0.756～0.874,P<0.001)and calibration ability(C index=0.794).Conclusion The nomogram established in this study has a good predictive ability for moderate-to-severe WMH in middle-aged and elderly patients with hypertension and can provide certain help for clinical workers.
White matter hyperintensityMagnetic resonance imagingNomogramInfluencing factor
国家科技期刊平台
NSTL
万方数据
维普
