摘要
帕金森病(Parkinson disease,PD)是多巴胺能神经元变性丢失引起的以运动迟缓、肌强直、静止性震颤和步态姿势异常为主要表现的神经系统变性疾病.临床上以药物治疗为主,但长期药物治疗可引起运动波动和多巴胺失调综合征,而运动锻炼作为PD的辅助治疗,可贯穿PD治疗的始终,不仅能改善患者的运动症状、非运动症状,还能减少PD的药物剂量及不良反应.近年来,运动锻炼已成为国内外PD治疗关注的热点,包括太极、八段锦、虚拟现实、舞蹈、瑜伽、渐进抗阻力训练、水疗以及有氧跑步机锻炼等.本文将对以上运动锻炼对PD的作用做一综述.
Abstract
Parkinson disease(PD)is a neurodegenerative disease caused by the degeneration and loss of dopaminer-gic neurons and is characterized by bradykinesia,myotonia,resting tremor,and abnormal gait and posture.Medication has been the main therapy for PD in clinical practice;however,long-term medication can cause motor fluctuations and do-pamine dysregulation syndrome.Exercise,as an adjuvant therapy for PD that runs through the whole process of PD treat-ment,can not only improve the motor and non-motor symptoms of PD patients,but also reduce the dose and adverse reac-tions of drugs for PD.In recent years,exercise has become a hot topic in PD treatment in China and globally,including tai chi,Baduanjin exercise,virtual reality,dance,yoga,progressive resistance training,hydrotherapy,and aerobic tread-mill exercise.This article reviews the effect of the above exercises on PD.
国家科技期刊平台
NSTL
维普
万方数据