Cytomegalovirus(CMV)ventriculoencephalitis is a type of severe encephalitis caused by CMV infection of the ependyma and brain parenchyma,with the main clinical manifestations of fever,headache,disturbance of con-sciousness,and convulsions.The opportunistic infection of CMV often occurs in immunocompromised people,mainly in patients with acquired immune deficiency syndrome(AIDS),while nervous system infection is extremely rare in people with competent immune function.This article reports a case of CMV ventriculoencephalitis in a non-AIDS young male pa-tient,with pyrexia and disturbance of consciousness as the initial presentation.Contrast-enhanced magnetic resonance im-aging showed a typical enhanced signal shadow of the ventriculomeninges,and a confirmed diagnosis was made based on cerebrospinal fluid CMV examination.We hope that this case of non-AIDS-related CMV ventriculoencephalitis will pro-vide help for clinicians to improve their understanding of the clinical and imaging manifestations of this disease.
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