Primary central nervous system lymphoma with positive anti-GFAP antibody in cerebrospinal fluid:a case re-port
This article reports a case of primary central nervous system lymphoma(PCNSL).The patient was a young man with subacute onset,and the disease lasted for more than 8 months and had the main manifestations of gradu-ally aggravated headache and dizziness.Cranial MRI showed ventricular dilatation,hydrocephalus,and meningeal en-hancement.Dehydration treatment aiming to reduce intracranial pressure alleviated the symptom of headache in the early stage of the disease;the cerebrospinal fluid was tested positive for anti-GFAP antibodies,and the symptoms were im-proved temporarily after hormone treatment.However,the symptom of headache aggravated again after hormone reduc-tion.Finally,the patient was diagnosed with PCNSL based on cerebrospinal fluid cytology and cerebrospinal fluid immuno-cytochemistry staining.
Primary central nervous system lymphomaCerebrospinal fluid cytologyAnti-GFAP antibody
万方数据
维普
