Relationship between changes in female reproductive status and objective sleep measures:a study based on poly-somnography
Objective To compare the general conditions,clinical characteristics,and polysomnographic features of patients before,around,and after menopause.Methods Participants were divided into premenopausal,perimenopausal,and postmenopausal groups by the age of 45 years and 55 years.General conditions,clinical characteristics,and polysomno-graphic indicators were compared across these groups.Results A total of 316 patients before,around,and after menopause were included in this study.There were no significant between-group differences in the body mass index,smoking and alco-hol consumption rates,sleep latency,sleep duration,sleep efficiency,and the durations and proportions of deep and light sleep.The perimenopausal and postmenopausal groups showed significantly increased nocturnal awakenings and significantly decreased nocturnal oxygen saturation compared with the premenopausal group.The apnea-hypopnea index(AHI)differed significantly between the three groups,showing an increasing trend.Conclusion Changes in reproductive status do not al-ter objective sleep duration and efficiency,and subjective perception contributes more to sleep disturbances around meno-pause.Changes in nocturnal sleep continuity,the AHI,and nocturnal minimum oxygen saturation suggest complex neuro-molecular mechanisms underlying the effects of hormonal variations on sleep in women.
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