The effect of CT perfusion imaging combined with galectin-3 in the diagnosis of mediastinal lymph node metasta-sis in preoperative lung cancer
Objective To investigate the characteristics of the occlusion site and the short-term prognosis of endo-vascular therapy in patients with acute vertebrobasilar artery occlusion caused by intracranial atherosclerosis and embolism based on computed tomography.Methods A total of 140 patients with acute vertebrobasilar artery occlusion treated in our hospital from January 2019 to May 2022 were selected.According to the pathological mechanism,there were 98 cases of atherosclerosis(group A)and 42 cases of embolism(group B).The clinical data,occlusion site,and prognosis of the two groups were compared using the t-test or χ2 test,and the differences in the clinical data of patients with different out-comes were analyzed.Receiver operating characteristic(ROC)curves were used to determine the value of the National In-stitutes of Health Stroke Scale(NIHSS)score and the Basilar Artery on Computed Tomography Angiography(BATMAN)score for predicting poor prognosis.Results There were no significant differences between group A and group B in sex,age,the body mass index,hypertension,diabetes,history of stroke,time from onset to admission,NIHSS score,and BATMAN score(P>0.05).The occlusion rates of the vertebral artery V4 segment and the middle basilar artery in group A were 41.84%and 33.67%respectively,which were significantly higher than those in group B(P<0.05).The propor-tion of upper basilar artery occlusion in group B was 59.52%,which was significantly higher than that in group A(P<0.05).The ischemic penumbra volume and infarct core volume in group A were(46.64±15.44)ml and(20.10±9.92)ml,respectively,which were significantly lower than those in group B(P<0.05).Patients with a poor prognosis had a signifi-cantly higher NIHSS score(24.41±2.09)points and a significantly lower BATMAN score(3.61±0.72)points than pa-tients with a good prognosis(P<0.05).For NIHSS score and BATMAN score predicting a poor prognosis,the areas under the ROC curves were 0.893 and 0.902,the cut-off values were 22 and 5,the sensitivity values were 86.60%and 92.70%,and the sensitivity values were 86.20%and 77.60%,respectively.Conclusion Patients with acute vertebro-basilar artery occlusion caused by intracranial atherosclerosis and embolism differ significantly in the occlusion site,but with no significant difference in the prognosis of patients.The NIHSS score and BATMAN score have certain application value in predicting the prognosis of patients with acute vertebrobasilar artery occlusion.
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