摘要
脑小血管病(CSVD)指的是一组临床、影像学和病理综合征,主要涉及颅内小动脉、微动脉、毛细血管和小静脉,好发于老年人群,因其发病隐匿,目前对其诊断和治疗常不及时,从而导致预后不良,常发展为认知障碍与行为障碍等.本文从脑小血管病及其导致的认知障碍目前研究发现的发病机制、影像征象、诊断、治疗几个方面进行阐述,以期引起临床上对脑小血管病早期诊断和早期治疗的重视.
Abstract
Cerebral small vessel disease(CSVD)refers to a group of clinical,imaging,and pathological syn-dromes,mainly involving intracerebral small arteries,arterioles,capillaries,and small veins.It is commonly observed in the elderly population,and its insidious onset often causes the delay in diagnosis and treatment,which may lead to poor prognosis and progression to cognitive and behavioral impairments.This article elaborates on the pathogenesis,imaging features,diagnosis,and treatment of CSVD and CSVD-induced cognitive impairment,in order to raise the awareness of early diagnosis and treatment of CSVD in clinical practice.