Research advances in blood biomarkers for cerebral small vessel disease
Cerebral small vessel disease(CSVD)is a dynamic vascular disease of the cerebrovascular system caused by various etiologies,resulting in a series of clinical,imaging,and pathological manifestations.With the increase in human life expectancy,CSVD has attracted much attention due to its high incidence and recurrence rates.With the re-search advances in imaging and neurophysiology,some progress has been made in the pathogenesis,diagnosis,and treat-ment of CSVD.Currently,researchers have found that the study of blood biomarkers for CSVD may help to achieve early diagnosis and intervention and improve prognosis.In addition,the accessibility,simplicity,and convenience of blood bio-markers make them promising for wide clinical application.This article reviews the research advances in blood biomarkers for CSVD.
Cerebral small vessel diseaseBiomarkerProteinGenePlasma metabolites