Ferroptosis is a newly discovered iron-dependent form of non-apoptotic cell death and is involved in the pathological process of many diseases.Intracerebral hemorrhage is a disease with high morbidity,mortality,and disability rates and is a common acute and critical illness in the department of neurology,and it often has a poor prognosis and greatly threatens human health.Primary brain tissue injury caused by intracerebral hemorrhage and secondary injury asso-ciated with cytotoxicity,neuroinflammation,and oxidative stress are the main reasons leading to poor prognosis,among which secondary brain injury after intracerebral hemorrhage is a difficulty in clinical treatment at present.Studies have shown that ferroptosis is closely associated with the course of secondary brain injury after intracerebral hemorrhage.In-depth research on the mechanism of ferroptosis after intracerebral hemorrhage and the prospect of drug therapies will pro-vide new ideas and new targets for the diagnosis and treatment of secondary brain injury after intracerebral hemorrhage.
国家科技期刊平台
NSTL
万方数据
维普
