Epilepsy is often comorbid with other neuropsychiatric conditions,which are known as epilepsy comor-bidities.Among these conditions,the comorbidity of epilepsy and migraine is very common.Although they are two differ-ent diseases,they overlap in terms of pathophysiological features and clinical symptoms,and several anti-seizure medica-tions(ASMs)have been proved to be effective in migraine.However,there are still controversies over the concept of epi-lepsy comorbid with migraine,and there is often a lack of effective treatment for migraine due to missed diagnosis or misdi-agnosis.In order to improve the ability for identification and precise treatment of epilepsy comorbid with migraine among clinicians,this article elaborates on the possible mechanism of epilepsy comorbid with migraine and discusses the con-cept,identification,and diagnosis and treatment regimens for epilepsy comorbid with migraine by considering the tempo-ral association between headache symptoms and epileptic seizures,with reference to the classification of epilepsy comorbid with migraine and related diagnostic criteria in Chinese expert consensus(2019)and the ICHD-3-2018 guidelines issued by the International Headache Society.
国家科技期刊平台
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