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药物过度使用性头痛研究现状

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原发性头痛疾病的药物过度使用是一种世界性的现象,在头痛疾病的慢性化中起着重要作用。由于其治疗高成本且常与多种疾病构成共病,个人和社会的疾病负担非常大。在国际头痛疾病分类第三版中,药物过度使用性头痛(MOH)被认为是继大多数原发性头痛疾病之外的一个独立的继发性实体。本文就药物过度使用性头痛的概述、流行病学、病理生理学机制、诊断标准和治疗方案进行综述,探讨了相关的未解问题,并总结了当前关于药物过度使用性头痛的争论。
The current status of medication overuse headache
The overuse of medications for primary headache disorders is a worldwide phenomenon that plays an im-portant role in the chronicity of headache disorders.The high treatment cost and co-morbidity with various diseases pose a heavy burden on individuals and societies.In the third edition of the International Classification of Headache Disorders,medication overuse headache(MOH)is recognized as a separate secondary entity to most primary headache disorders.This article reviews the overview,epidemiology,pathophysiological mechanisms,diagnostic criteria,and treatments of MOH,discusses some unsolved questions,and summarizes the current debate on MOH.

Medication overuse headacheSecondary headacheResearch statusAnnexin A1Chronic headache

安悦铭、于生元

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解放军总医院第一医学中心神经内科医学部,北京 100853

药物过度使用性头痛 继发性头痛 研究现状 膜联蛋白A1 慢性头痛

2024

中风与神经疾病杂志
吉林大学

中风与神经疾病杂志

CSTPCD
影响因子:0.754
ISSN:1003-2754
年,卷(期):2024.41(7)