缺血性卒中侧支循环的生物标志物的研究进展
Research advances in biomarkers for collateral circulation in ischemic stroke
张思敏 1余传庆1
作者信息
- 1. 安徽理工大学第一附属医院(淮南市第一人民医院)神经内科,安徽 淮南 232007
- 折叠
摘要
缺血性卒中是因脑血管闭塞或者狭窄导致脑血流灌注下降,进而临床上表现出一些神经功能缺失症状的一类疾病总称,具有高发病率、高致残率、高死亡率以及高复发率的特性.当缺血性卒中发生时,血液通过其他开放或者新生的血管到达缺血区,从而代偿缺血组织,这些开放的血管吻合支或新生的血管统称为脑侧支循环,目前影像检查是评价侧支循环的主要方法,但受技术条件的限制.一些研究发现,生物标志物对侧支循环的状态及形成具有重要的提示意义,本文主要就缺血性卒中侧支循环生物标志物的研究进展进行综述.
Abstract
Ischemic stroke is a group of diseases with the clinical manifestation of neurological deficits due to a re-duction in cerebral blood perfusion caused by occlusion or narrowing of cerebral blood vessels,with the characteristics of high incidence rate,high disability rate,and high mortality rate.When ischemic stroke occurs,blood reaches the isch-emic area through other open or new vessels to compensate for the ischemic tissue,and such open anastomotic branches or new vessels are collectively referred to as cerebral collateral circulation.At present,imaging examination is the main method for evaluating collateral circulation,but it is still limited by certain technical issues.Several studies have shown that biomarkers are important in reflecting the status and formation of collateral circulation,and this article reviews the re-search advances in the biomarkers for collateral circulation in ischemic stroke.
关键词
缺血性卒中/侧支循环/生物标志物Key words
Ischemic stroke/Collateral circulation/Biomarkers引用本文复制引用
基金项目
高等学校省级质量工程项目(2022jcjs037)
出版年
2024
国家科技期刊平台
NSTL
万方数据