Application value of intracranial arterial calcification in mechanical thrombectomy for acute ischemic stroke
Objective To investigate the modified Woodcock score of intracranial arterial calcification(IAC)in acute ischemic stroke patients with intracranial large or medium vessel occlusion and its impact on the outcome of endovascular treatment and surgery.Methods The patients who underwent mechanical thrombectomy for acute isch-emic stroke due to large or medium vessel occlusion in our hospital from January 2017 to July 2021 were enrolled,and related demographic and clinical variables were analyzed,including age,sex,and National Institutes of Health Stroke Scale(NIHSS).Pearson correlation analysis,linear regression analysis,and logistic regression analysis were used for modeling to determine the association between symptomatic IAC and outcome,and the variables that were sig-nificantly associated with outcome were used for adjustment,with P<0.05 as statistically significant.Results Of all acute ischemic stroke patients,74(53.6%)were found to have intracranial vascular calcification on CT images on admission.The modified Woodcock score on the ipsilateral side of the diseased vessels had a certain value in predict-ing the prognosis of mechanical thrombectomy for large vessel occlusion,and the logistic regression analysis showed that calcification score on the ipsilateral side was negatively correlated with the modified Rankin Scale(mRS)score(P=0.026),and the use of balloons was positively correlated with mRS score(P=0.035).Data analysis showed that the patients with a high level of low-density lipoprotein(LDL)tended to have high total hospital costs,high costs of surgical materials,a high possibility of stent implantation,and a low recanalization rate.Conclusion Intracranial arterial calcification score has a certain application value in mechanical thrombectomy for acute ischemic stroke.Pa-tients with high LDL tend to have high total hospital costs,high costs of surgical materials,a high possibility of stent implantation,and a low recalculation rate after surgery.