Research advances in the association of cerebral small vessel disease with vascular reserve and cognitive impair-ment
The incidence rate of cerebral small vessel disease(CSVD)is increasing year by year,and early screen-ing,diagnosis,and treatment of CSVD is of great significance.Cognitive impairment is one of the manifestations of CSVD that have a great impact on the quality of life of patients.Transcranial Doppler(TCD)can early judge the vascular reserve capacity of patients with CSVD,and the total MRI load of CSVD can calculate the degree of CSVD lesions more compre-hensively than that of independent lesions.This article reviews the research advances in the association of CSVD with total MRI load,vascular reserve,and cognitive impairment in CSVD patients and elaborates on the early screening,diagnosis,and treatment of CSVD.
Cerebral small vessel diseaseTotal MRI loadVascular reserveCognitive impairment