中国病理生理杂志2024,Vol.40Issue(1) :187-192.DOI:10.3969/j.issn.1000-4718.2024.00.001

间充质干细胞衍生的细胞外囊泡在调控心肌缺血再灌注损伤中的研究进展

Progress in role of mesenchymal stem cell-derived extracellular vesicles in regulating myocardial ischemia-reperfusion injury

谭景锐 江永鑫 王诗源
中国病理生理杂志2024,Vol.40Issue(1) :187-192.DOI:10.3969/j.issn.1000-4718.2024.00.001

间充质干细胞衍生的细胞外囊泡在调控心肌缺血再灌注损伤中的研究进展

Progress in role of mesenchymal stem cell-derived extracellular vesicles in regulating myocardial ischemia-reperfusion injury

谭景锐 1江永鑫 2王诗源1
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作者信息

  • 1. 山东中医药大学,山东 济南 250000
  • 2. 江高镇卫生院,广东 广州 510080
  • 折叠

Abstract

Currently,revascularization is an effective rescue strategy for patients with acute myocardial infarc-tion.However,myocardial ischemia/reperfusion(I/R)injury induced by revascularization has become a significant risk factor affecting the long-term prognosis of patients with ischemic cardiomyopathy after revascularization,without precise treatment.Extracellular vehicles derived from mesenchymal stem cells are characterized by easy access,editability,and easy absorption of cells,and their application in treating myocardial I/R injury is considered valuable to study.This review focuses on the advances in research on mesenchymal stem cell-derived extracellular vehicles and their function of regulating myocardial I/R injury after natural drug intervention,hopefully offering ideas for the research of prevention and treatment of myocardial I/R injury.

关键词

心肌缺血/再灌注损伤/间充质干细胞/细胞外囊泡

Key words

myocardial ischemia/reperfusion injury/mesenchymal stem cells/extracellular vehicles

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基金项目

山东省自然科学基金资助项目(ZR2020MH352)

出版年

2024
中国病理生理杂志
中国病理生理学会

中国病理生理杂志

CSTPCD北大核心
影响因子:1.065
ISSN:1000-4718
参考文献量4
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