摘要
食欲调节系统通过促进/抑制食欲神经元/因子,在促进新陈代谢、调节能量、维持体重等方面发挥着重要作用.近年来的研究表明,食欲调节系统可直接影响多种与高血压相关的病理生理机制,包括交感神经兴奋、水钠潴留、血管损伤、氧化应激等.本文就中枢食欲神经元、中枢食欲因子和外周食欲因子在高血压中的作用进行综述.
Abstract
The appetite regulation system is important for improving metabolism,regulating energy,and maintaining body weight by promoting/inhibiting appetite neurons/factors.Recent studies have shown that the appetite reg-ulation system can directly affect various hypertension-related pathophysiological processes,including sympathetic excita-tion,water and sodium retention,vascular damage,and oxidative stress.This review summarizes the roles of central appe-tite neurons,central appetite factors,and peripheral appetite factors in the pathogenesis of hypertension.
基金项目
国家自然科学基金(82160886)
甘肃省自然科学基金优秀博士生项目(22JR5RA579)
甘肃省省级重点人才项目(甘组通字[2023]20号)