Progress in relationship between expression of solute carrier family 3 member 2,and disulfidptosis,ferroptosis and tumors
Ferroptosis and disulfidpthosis are associated with various diseases.Ferroptosis is distinguished by abnormal accumulation of iron ions and lipid reactive oxygen species,while disulfidptosis is marked by abnormal accumu-lation of disulfides.Solute carrier family 3 member 2(SLC3A2),a component of the solute carrier family,is implicated not only involved in the regulation of tumor cell proliferation,migration,invasion and apoptosis,but also in the processes of ferroptosis and disulfidptosis,playing a pivotal role in tumor growth and progression.This article provides an overview of the latest advancements in understanding the relationship between SLC3A2 and ferroptosis,disulfidptosis and tumors,aiming to establish a theoretical basis for targeted cancer therapies.
solute carrier family 3 member 2disulfidptosisferroptosistumor