热激转录因子HSF调控植物非生物胁迫响应的作用机制
The Mechanisms of Heat Shock Transcription Factors(HSF)Regulating Plant Response to Abiotic Stress
伍国强 1张佳乐 1魏明1
作者信息
- 1. 兰州理工大学生命科学与工程学院,甘肃 兰州 730050
- 折叠
摘要
热激转录因子(Heat shock transcription factors,HSF)是植物抵抗热胁迫最重要的转录因子家族之一,广泛存在于真核生物.HSF拥有高度保守的DNA结合域,可参与复杂的胁迫信号转导和响应网络.HSF作为信号转导链的末端组分,介导非生物逆境胁迫下靶标基因的表达.在逆境胁迫响应中,HSF受上游蛋白激酶介导磷酸化和泛素化或通过ABA信号通路结合热激元件,调控热激蛋白等下游基因的表达,从而提高植物的抗逆性.本文综述HSF的发现、结构、分类、调控机制及其在植物响应非生物逆境胁迫(极端温度、干旱、高盐碱和重金属等)中的作用机制,并对未来研究方向加以展望,以期为农作物和牧草抗逆性遗传改良提供理论依据和基因资源.
Abstract
Heat shock transcription factor(HSF),widely found in eukaryotes,are one of the most cru-cial transcriptional factors families in the plant resistance to heat stress.HSF has highly conserved DNA-binding domain(DBD),which is involved in complex stress signal transduction and response networks.HSF,as a terminal component of the signal transduction chain,mediated the expression of target genes under abiotic stress.In response to stress,HSF is phosphorylated and ubiquitinated by upstream protein kinases or binds to heat shock elements(HSEs)through ABA signaling pathway to regulate the expression of downstream genes such as heat shock proteins(HSPs),thereby improving plant stress resistance.In this study,the discovery,structure,classification,regulatory mechanism of HSF and its role in plant response to abiotic stress(extreme temperature,drought,high salinity,heavy metal,et al.)were reviewed,and the future research direction was expected to provide theoretical basis and gene resources for the genetic improvement of crop and forage stress resistance.
关键词
热激转录因子/非生物逆境胁迫/调控机制/磷酸化/热激元件Key words
Heat shock transcription factors/Abiotic stress/Regulatory mechanism/Phosphoryla-tion/Heat shock elements引用本文复制引用
基金项目
国家自然科学基金项目(32360483)
国家自然科学基金项目(32160466)
甘肃省自然科学基金重点项目(23JRRA764)
出版年
2024
NETL
NSTL
万方数据