Meta-analysis of clinical randomized controlled trials of Hedan Tablets in the treatment of coronary heart disease
Objective To systematically evaluate the efficacy and safety of Hedan Tablets in the treatment of coronary heart disease.Methods Two researchers systematically searched the literature on the treatment of coronary heart disease with Hedan Tablets,clinical randomized controlled trials on Hedan Tablets in the treatment of coronary heart disease were included in CNKI,China Academic Journal Database(CSPD),Wanfang Database,VIP Chinese Science and Technology Journal Full-text Database(CCD),the Cochrane Library,PubMed.Two researchers independently collated the literature and evaluated the quality of the literature.The retrieval time was before September 2022.Results A total of 9 eligible studies were included,involving 837 patients.Meta-analysis results showed that the efficacy,lipid levels and inflammatory factors before and after treatment were better in the treatment group than in the control group,and adverse reactions were mentioned in one study.Conclusion The clinical efficacy of Hedan Tablet in the treatment of coronary heart disease is better than that of conventional treatment group.Hedan Tablets can reduce the blood lipid level in patients with coronary heart disease,and regulate the inflammatory factors such as TNF-a,IL-6 and hs-CRP in patients with coronary heart disease.Hedan Tablet is effective in the treatment of coronary heart disease and can provide clinical treatment ideas.