Comparison of pregnancy effect of different ovulation induction schemes combined with ultrasound and LH peak monitoring in PCOS patients
Objective To compare the effectiveness of endometrial receptivity,monitoring follicle development and luteinizing hormone(LH)monitoring in patients with polycystic ovarian syndrome(PCOS).Methods A total of 120 PCOS patients admitted to our hospital from October 2020 to September 2022 were selected.Patients were divided into the control and the observation group according to the random number table method,with 60 patients in each group.Clomifene(CC)and urocin(HMG)were used for ovulation as the control group,and letrozole(LE)and HMG for ovulation as the observation group.Combined with transvaginal color Doppler ultrasound,the endometrial receptivity,human chorionic gonadotropin(HCG)daily examination of follicle stimulating hormone(FSH),estradiol(E2),LH levels,ovulation rate and pregnancy prognosis of the two groups of patients were compared before and after treatment.Results Before treatment,the endometrial receptivity of the two groups was comparable(P＞0.05),while the levels of FSH and LH on HCG days were comparable(P＞0.05),and the ovulation rate was comparable(P＞0.05).After treatment,the endometrial receptivity of the observation group was significantly better than that of the control group:endometrial thickness,endometrial echo type A,endometrial volume,vascularization index(VI),blood flow index(FI),and vascularization blood flow index(VFI)levels were higher than those of the control group,with statistical significance(P＜0.05);After treatment,the observation group had lower endometrial echo C-type,pulsatile index(PI),resistance index(RI),uterine artery blood flow spectrum systolic/diastolic peak ratio(S/D),and E2 levels compared to the control group,with statistical significance(P＜0.05).The observation group had thicker endometrial thickness in the middle and late follicular stages compared to the control group(P＜0.05),and the pregnancy rate in the observation group was significantly higher than that in the control group(P＜0.05).Conclusion Compared to CC combined with HMG for ovulation induction,LE combined with HMG improves endometrial receptivity,resulting in a higher pregnancy rate and better pregnancy assistance effect.
ClomipheneLetrozolePatients with polycystic ovary syndromeTransvaginal color Doppler ultrasoundLuteinizing hormone
NETL
NSTL
万方数据
维普
