Analysis of the clinical application of pregabalin in a hospital
Objective Standardize the clinical application of pregabalin.Methods Using the rational drug use system(PASS)of our hospital,the outpatient prescriptions(1 397)and ward doctor's orders(322)of pregabalin from January to December 2022 were retrieved,and their clinical use was counted and reviewed one by one.Results Most of the patients using pregabalin were middle-aged and elderly,there were more female patients in the outpatient clinics than in the ward,and the department with the highest utilization rate in the hospital was neurology.The results of the pregabalin review showed that 172(12.31％)of unreasonable prescriptions were used in outpatient clinics,and 62(19.25％)of medical orders were used in wards.The unreasonable use mainly focuses on inappropriate indications and unreasonable usage and dosage,and there were still irregularities in clinical diagnosis writing and repeated medication in outpatient clinics.Off-label drug use:579 patients(41.45％)in outpatient clinics and 191 patients(59.32％)in wards,mainly using pregabalin to treat peripheral and central neuropathic pain associated with various diseases,anxiety,epilepsy,restless leg syndrome and so on,but off-label medication management was not in place.Conclusion The use of pregabalin in our hospital is reasonable,off-label medication is common,but off-label drug use management is not in place.Clinicians should issue prescriptions and medical orders in accordance with specifications,and clinical pharmacists should strictly review prescriptions beforehand and make comments afterwards, assist hospitals in implementing off-label drug use management, and promote clinical standardization of drug use.
万方数据
维普
