首页|加味升陷汤联合体外膈肌起搏治疗COPD合并Ⅱ型呼吸衰竭的临床效果观察

加味升陷汤联合体外膈肌起搏治疗COPD合并Ⅱ型呼吸衰竭的临床效果观察

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目的 探究加味升陷汤联合体外膈肌起搏(EDP)治疗慢性阻塞性肺疾病(COPD)合并Ⅱ型呼吸衰竭的临床效果。方法 采用随机数字表法将 2022 年 1 月~2023 年 5 月收治的 64 例COPD合并Ⅱ型呼吸衰竭患者分为观察组(n= 32)和对照组(n= 32)。两组均予常规西医治疗,观察组加用加味升陷汤联合EDP治疗。治疗 5 d后,对比两组右侧膈肌位移和膈肌增厚分数、血气分析、炎症指标。结果 治疗后两组右侧膈肌指标、氧合指数均提高,且观察组高于对照组(P<0。05)。治疗后两组动脉血二氧化碳分压、炎症指标均下降,且观察组低于对照组(P<0。05)。结论 在常规治疗基础上联合加味升陷汤、EDP治疗,可有效改善COPD合并Ⅱ型呼吸衰竭患者的膈肌功能、氧合指数、炎症指标,促进二氧化碳排出,缓解病情。
Curative Effect observation of modified Shengxian Decoction combined with external diaphragm pacing for treating chronic obstructive pulmonary disease with type Ⅱ respiratory failure
Objective To explore the clinical effect of modified Shengxian Decoction combined with external diaphragm pacer(EDP)in the treatment of chronic obstructive pulmonary disease(COPD)with type Ⅱ respiratory failure.Methods From January 2022 to May 2023,64 patients with COPD complicated with type Ⅱ respiratory failure were divided into observation group(n = 32)and control group(n = 32)by random number table method.Both groups were treated with conventional western medicine,and the observation group was treated with modified Shengxian Decoction combined with EDP.After 5 days of treatment,the right diaphragmatic excursion and diaphragm thickening fraction,blood gas analysis and inflammatory indexes were compared between the two groups.Results After treatment,the right diaphragm index and oxygenation index of the two groups increased,and those indexes in the observation group were higher than the control group(P<0.05).After treatment,the arterial partial pressure of carbon dioxide and inflammatory indexes of the two groups decreased,and those indexes in the observation group were lower than the control group(P<0.05).Conclusion On the basis of conventional treatment,the combination of modified Shengxian Decoction and EDP can effectively improve the diaphragmatic function,oxygenation index and inflammatory index of COPD patients with type Ⅱ respiratory failure,promote the discharge of carbon dioxide and alleviate the condition.

Shengxian DecoctionExternal diaphragm pacerChronic obstructive pulmonary diseaseNoninvasive mechanical ventilationDiaphragmatic function

刘玲、杨桃花、李振龙

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湖南中医药大学,长沙 410208

郴州市中医医院重症医学科,湖南郴州 423000

湖南中医药大学附属常德医院重症医学科,湖南常德 415000

升陷汤 体外膈肌起搏 慢性阻塞性肺疾病 无创机械通气 膈肌功能

湖南省中医药科研计划项目

D2022062

2024

中国处方药
南方医药经济研究所

中国处方药

影响因子:0.649
ISSN:1671-945X
年,卷(期):2024.22(1)
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