Analysis of traditional Chinese medicine syndromes and related factors in primary hepatobiliary malignancies treated with traditional Chinese medicine
Objective To explore the distribution of Chinese medicine patterns in patients with primary hepatobiliary malignancies treated with Chinese medicine adjuvant therapy and the correlation between factors such as gender,age,surgical history,treatment history,and whether distant metastasis occurred and the distribution of patterns.Methods The clinical data of patients with primary hepatobiliary malignancies who were hospitalized in a hospital to receive Chinese medicine-assisted treatment from January 2018 to February 2023 were retrospectively analyzed,and the distribution pattern of Chinese medicine patterns and the correlation between factors such as general information,surgical history,and treatment history and Chinese medicine patterns were studied using statistical software.Results A total of 60 patients were included in the study,and the distribution pattern of Chinese medicine patterns was as follows:liver depression and spleen deficiency pattern＞qi stagnation and blood stasis pattern＞liver and gallbladder damp-heat pattern＞liver and kidney yin deficiency pattern＞water-dampness internal stagnation pattern,and the differences in the distribution of Chinese medicine patterns in terms of history of chemotherapy,history of targeted therapy,history of immunotherapy,and whether or not lymph node metastasis had occurred were statistically significant(P＜0.05),while the differences in the distribution in terms of gender,age,history of surgery,and whether or not distant metastasis had occurred were not statistically significant(P＞0.05).Multivariate regression analysis found that whether or not immunotherapy was an independent factor affecting the evidence of liver depletion and spleen deficiency,and whether or not chemotherapy,whether or not immunization,and whether or not lymph node metastasis were independent factors affecting the evidence of qi stagnation and blood stasis.Conclusion The Chinese medicine patterns of patients with primary hepatobiliary malignancies treated with adjuvant Chinese medicine were predominantly of the liver-depression and spleen-deficiency pattern and the qi stagnation and blood stasis pattern;the patients'treatment history and the presence of lymph node metastasis were related to the distribution of the Chinese medicine patterns;the receipt of chemotherapy or immunotherapy increased the risk of the appearance of the qi stagnation and blood stasis pattern.
Primary hepatobiliary malignanciesTraditional Chinese medicine syndromesRelated factors
万方数据
维普
