Effect of Huayu Qingre Decoction combined with Xipayi solid gingival solution on recurrence of oral lichen planus patients
Objective To explore the effect of Huayu Qingre Decoction combined with Xipayi solid gingival solution on the recurrence of oral lichen planus patients.Methods A total of 100 oral lichen planus patients treated in a hospital from July 2021 to August 2023 were selected and divided into the control group(n= 50)and the observation group(n= 50)according to random number method.The control group was treated with Xipayi solid gingival solution,and the observation group was treated with Huayu Qingre Decoction combined with Xipayi solid gingival solution.Oral mucosal symptom area,inflammatory factors,hemorheology,pain degree and recurrence rate were compared between the two groups to evaluate the clinical efficacy.Results The total effective rate of the observation group was higher than that of the control group(P＜0.05).After treatment,the symptomatic area of oral mucosa in the observation group was smaller than that in the control group(P＜0.05).After treatment,the levels of inflammatory factors and hemorheology indexes in the observation group were lower than those in the control group(P＜0.05).After treatment,the pain degree score of the observation group was(0.65±0.13)points,which was significantly lower than that of the control group(0.97±0.24)points,with significant difference(P＜0.001).After one year of follow-up,the recurrence rate of the observation group(6.00%)was significantly lower than that of control group(22.00%),with significant difference(P = 0.021).Conclusion In the treatment of oral lichen planus patients,Huayu Qingre Decoction combined with Xipayi solid gingival solution has a relatively good effect,which can improve the hemorheology and inflammation of patients,and reduce the recurrence rate and pain degree of patients.
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