Risk factors for airway obstruction after drug induced sleep
Objective To explore the risk factors of airway obstruction after drug induced sleep.Methods A prospective selection was con-ducted on 100 patients who underwent elective surgery in our hospital from February 2021 to March 2023.After entering the room and successfully inducing sleep with medication,sleep endoscopy was used to observe the airway obstruction status of the patients.Based on the results,all patients were divided into two groups:the group with airway obstruction and the group without airway obstruction.General data and intraoperative related information were collected from the two groups,and multiple factor Logistic regression analysis was used to analyze the factors affecting airway obstruction,draw ROC curve and calculate AUC.Results 58 cases of airway obstruction occurred,while 42 cases did not occur;Multivariate Logistic regression analysis showed that age(OR=1.092,95%CI:1.011~1.180),frequency of apnea(OR=7.584,95%CI:1.629~35.312),frequency of low ventilation(OR= 1.922,95%CI:1.257~2.940),and dosage of midazolam(OR= 1.284,95%CI:1.019~1.618)were risk factors for airway obstruction(P<0.05);Incorporating multiple influencing factors for ROC curve analysis showed that age(AUC = 0.764,95%CI:0.668~0.843);dosage of midazolam(AUC= 0.593,95%CI:0.491~0.691);hypoventilation frequency(AUC= 0.880,95%CI:0.799~0.936);the number of apnea episodes(AUC= 0.890,95%CI:0.811~0.943).Conclusion The frequency of low ventilation,age,frequency of apnea,and the dosage of midazolam after drug induced sleep are risk factors for airway obstruction in patients.