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一例阿奇霉素抗感染治疗导致过敏的药学分析

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目的 观察并分析 1 例支原体肺炎的患儿在输注阿奇霉素粉针和氨溴索注射液时先后 2 次出现了皮疹的情况,为临床合理安全使用阿奇霉素提供参考。方法 分析 1 例支原体肺炎感染患儿的病历资料,该患儿入院第 1 日在阿奇霉素粉针输注近完毕时发现其左侧上臂内侧皮肤出现散在风团立即予以停用,入院第3日患儿输注氨溴索注射液约10 min后出现口唇水肿,左侧下肢出现散在风团皮疹。患儿先后 2 次出现了过敏反应,因阿奇霉素粉针和氨溴索注射液导致的过敏反应报道的较少,研究该患儿过敏反应的发生与输注药品之间的关系。结果 该患儿输注的阿奇霉素粉针与前后 2 次出现过敏反应有一定的因果关系。结论 阿奇霉素出现过敏反应时即使停止输注也有可能出现二次过敏反应的发生,所以当输注阿奇霉素出现过敏反应时需要长时间的观察和持续的对症治疗。
Pharmaceutical analysis of a case of allergy caused by azithromycin anti infection treatment
Objective To observe the rash of a child with mycoplasma pneumonia who was injected with azithromycin powder injection and ambroxol injection twice and can provide a reference for the rational and safe use of azithromycin in clinical practice.Methods The medical records of a child with mycoplasma pneumonia infection were analyzed.On the first day of admission,when the injection of azithromycin powder injection was nearly completed,the child was found to have scattered wheals on the medial skin of his left upper arm and was immediately stopped.On the third day of admission,the child had mouth and lip edema after about 10 minutes of ambroxol injection,and scattered wheals on the left lower limb.The child had allergic reactions twice,and there were few reports of allergic reactions caused by azithromycin powder injection and ambroxol injection.The relationship between the occurrence of allergic reactions in the child and the infusion of drugs was studied.Results It was found that there was a certain causal relationship between the azithromycin powder injection and the anaphylaxis of the two times before and after the injection.Conclusion When azithromycin has allergic reactions,even if the infusion is stopped,secondary allergic reactions may occur.Therefore,when azithromycin infusion has allergic reactions,long-term observation and continuous symptomatic treatment are required.

AzithromycinRashAllergy

肖蔓

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周口市妇幼保健院(周口市儿童医院),河南周口 466000

阿奇霉素 皮疹 过敏

2024

中国处方药
南方医药经济研究所

中国处方药

影响因子:0.649
ISSN:1671-945X
年,卷(期):2024.22(3)
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