首页|新型长效重组人粒细胞集落刺激因子艾贝格司亭α临床应用

新型长效重组人粒细胞集落刺激因子艾贝格司亭α临床应用

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艾贝格司亭α是第 3 代新型长效重组人粒细胞刺激因子,为国家一类新药,具有提升中性粒细胞绝对计数(ANC)谷值,缩短ANC恢复时间的作用,可用于化疗引起的中性粒细胞减少的一级预防。本文就其发展历程、临床研究、适用条件、不良反应和新冠感染期的合并用药作一综述,以期为临床用药提供参考。
Clinical application of new recombinant human granulocyte colony stimulating factor Efbemalenograstim α
Efbemalenograstim α is the third generation of new recombinant human granulocyte colony stimulating factor,which is a Class 1 new drug in China.It can increase the valley value of absolute count of neutrophil(ANC)and shorten the recovery time of ANC.For primary prevention of chemotherapy-induced neutrophil reduction.This article reviews its development,clinical studies,application conditions,adverse drug reactions and combination therapies in the stage of covid-19 infection with a view to providing reference for clinical use.

Efbemalenograstim αGranulocyte colony stimulating factorMyelosuppressiveFebrile neutropenia

蒋媛、王美飒、史桂玲

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天津市人民医院药学部,天津 300121

艾贝格司亭α 粒细胞集落刺激因子 骨髓抑制 发热性中性粒细胞减少

天津市人民医院科研项目创新药物上市后临床研究科研专项

2022YJ025WKZX2023CX210003

2024

中国处方药
南方医药经济研究所

中国处方药

影响因子:0.649
ISSN:1671-945X
年,卷(期):2024.22(3)
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