Analysis of 41 cases of adverse drug reactions induced by etimicin
Objective To analyze the characteristics of and risk factors for adverse drug reactions(ADR)induced by etimicin and provide reference for clinical rational drug use.Methods 41 ADR reports of etimicin in the ADR monitoring database of Tai'an city(January 1,2008 to July 31,2023)were retrospectively analyzed.Results Among 41 ADR reports,8 cases(19.51%)were new general ADR,and 10 cases(24.39%)were severe ADR.There were 23 males and 18 females involved,most of them were aged 45～64 years and more than 65 years old.2 cases were reported to have a history of ADR.Most of the ADR occurred within 1 day of medication,the systems involved were mainly skin and its attachments,gastrointestinal system,central and peripheral nervous systems,and hepatobiliary system.The main clinical manifestations included itching,rash,nausea,vomiting,dizziness,headache,and elevation of transaminase.Conclusion The warning information of the instructions for etimicin is inadequate.Drug manufacturers need to strenthen the investigation of the post-marketing data and improve the instructions.Anaphylactic shock and other serious ADR should be added into the instructions.Clinic should pay attention to the risk of overdose for elderly patients and strengthen the monitoring of hepatic and renal function to ensure their medication safety.
EtimicinAverse drug reactionRetrospective analysisDrug instructions
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NSTL
万方数据
