Analysis of 120 adverse reactions of antituberculosis drugs in a hospital
Objective To investigate the characteristics and regularity of adverse reactions(ADR)of anti-tuberculosis drugs in a hospital,and provide reference for clinical treatment,reduce the occurrence of ADR.Methods Evaluate and analyze the ADR data of 120 antituberculosis drug of patients in the hospital from the perspectives of gender,age,route of administration,main drugs,organs/systems involved in ADR,and clinical manifestations.Results Among 120 ADR patients,there were 74 male(61.67%).The proportion of ADR reached 58.33%in patients over 50 years old.The proportion of ADR caused by intravenous administration reached 62.50%.Mild ADR account for 87.50%,new and mild ADR account for 10.83%,severe and new severe ADRs each account for 0.83%.The most affected organs or systems in ADR are the skin and its accessories,digestive system,and systemic reactions.Rifampicin and moxifloxacin caused most ADR of all.Conclusion Ensuring patient safety from the entire process of prevention,treatment and prognosis in clinical treatment,timely supplement and improve medication risk warnings;medical staff should strengthen ADR monitoring and reporting.
Adverse reactionsAntituberculosis drugsTuberculosisRational drug use
NETL
NSTL
万方数据
