Comparison of efficacy and safety between laparoscopic radical resection of low rectal cancer and traditional open surgery
Objective To observe the short-term efficacy and safety of laparoscopic radical resection of low rectal cancer and conventional open radical resection of rectal cancer.Methods 80 patients with low rectal cancer admitted to a hospital from April 2021 to April 2023 were divided into the observation group and the control group by random number table method,40 cases in each group.The observation group underwent laparoscopic radical resection of low rectal cancer,the control group underwent conventional laparotomy radical resection of rectal cancer.The perioperative indexes,circumferential margin status,anal preservation rate,postoperative recovery,serum inflammatory factor level and postoperative complication rate were compared between the two groups.Results There was no significant difference in operation time and number of lymph nodes dissection between the two groups(P＞0.05).The intraoperative blood loss of the observation group and the control group were(90.24±23.34)ml and(148.02±18.67)ml,and the incision length were(5.17±0.94)cm and(14.75±2.26)cm,respectively.The intraoperative blood loss and incision length of the observation group were less than those of the control group(P＜0.05).There was no significant difference in the positive rate of periannular margin and anal preservation between the two groups after surgery(P＞0.05).The first time of anal exhaust of the observation group and the control group were(2.07±0.85)d and(2.75±0.91)d,the time of catheter extraction were(2.21±0.67)d and(3.45±1.22)d,and the first time of getting out of bed were(4.55±1.17)d and(6.28±1.36)d,respectively.Postoperative hospitalization time of the observation group and the control group were(10.69±2.27)d and(12.86±3.61)d,and the observation group was shorter than the control group(P＜0.05).The levels of interleukin-6(IL-6)and cortisol(Cor)in the observation group and the control group after operation were(63.09±7.25)ng/L and(69.71±8.43)ng/L,respectively,and(328.95±41.75)μg/L and(451.37±53.62)μg/L.C-reactive protein(CRP)levels of the observation group and the control group were(22.64±7.78)mg/L and(34.51±11.92)mg/L,respectively,which were lower in observation group than control group(P＜0.05).The incidence of postoperative complications in the observation group and the control group were 5.00%and 20.00%,and the observation group was lower than the control group(P＜0.05).Conclusion Laparoscopic radical resection of low rectal cancer is similar to conventional open surgery in terms of operation time,number of lymph nodes dissection and anal preservation rate.However,laparoscopic radical resection of low rectal cancer is less invasive,conducive to reducing inflammation,reducing postoperative complications,and contributing to early postoperative rehabilitation.
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