Analysis of prognostic factors of early and middle stage triple negative breast cancer patients after modified radical mastectomy
Objective To analyze the prognostic factors of early and middle stage triple negative breast cancer patients after modified radical mas-tectomy.Methods A case-control study was conducted to select 40 cases of early and middle stage triple negative breast cancer patients with recurrence and metastasis after modified radical surgery in the hospital from January 2020 to January 2022 into the occurrence group,and 40 cases of early and middle stage triple negative breast cancer patients with no recurrence and metastasis in the hospital during the same period were collected into the non occurrence group.The tumor diameter,surgical margin width,disease type,lymph node metastasis and other data of the two groups were compared to explore the factors affecting the clinical prognosis of early and middle stage triple negative breast cancer patients after modified radical mastectomy.Results The tumor diameter,MFSI-SF score,and proportion of lymph node metastasis in the occurrence group were greater than those in the non occurrence group,and the proportion of postoperative immunotherapy was lower than that in the non occurrence group(P＜0.05).Logistic regression analysis showed that large tumor diameter,postoperative immunotherapy,lymph node metastasis,and high MFSI-SF score were the influencing factors of recurrence and metastasis in early and middle stage triple negative breast cancer patients after modified radical mastectomy(P＜0.05).Conclusion Patients with early and middle stage triple negative breast cancer have a certain risk of recurrence and metastasis after modified radical mastectomy.Large tumor diameter,postoperative immunotherapy,lymph node metastasis,and high cancer-related fatigue are the factors affecting its occurrence.
Triple negative breast cancerModified radical mastectomyRecurrence and metastasisInfluence factor
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