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超微粉碎对太子参粉理化性质和有效成分含量的影响

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目的 研究超微粉碎对太子参粉的理化性质及太子参环肽B含量的影响.方法 以太子参为原料,采用超微粉碎技术制备粉体,使用激光粒度仪、扫描电镜、粉体综合测定仪和质构仪进行理化性质研究,使用HPLC法测定太子参粉中环肽B的含量.结果 与细粉相比,超微粉碎后的太子参粉粒径减小,粉体流动性变差,填充性变大,水合性能增大,HPLC法测得超微粉碎粉体中太子参环肽B含量比细粉大.结论 超微粉碎技术可以影响太子参的理化性质,促进太子参环肽B的溶出.
Effect of ultramicro crushing on the physicochemical properties and active ingredient content of Radix Pseudostellaria powder
Objective To study the effect of ultrafine crushing on the physicochemical properties and the content of heterophyllin B of Radix Pseudostellaria powder.Methods The powders were prepared by ultramicrocrushing technique,using the laser particle size meter,scanning electron microscope,powder synthesis stable micro systems for the study of the powder physicochemical properties,and the content of heterophyllin B in the Radix Pseudostellaria powders was determined by HPLC method.Results Compared with the fine powder,the particle size of the ultramicrocrushed Radix Pseudostellaria powder decreased,the powder became less fluid,more filled,and the hydration property increased,and the content of heterophyllin B of Radix Pseudostellaria in the ultramicrocrushed powder was larger than that of the fine powder as measured by the HPLC method.Conclusion Ultramicrocrushing technology can affect the powder physicochemical properties of Radix Pseudostellaria and promote the dissolution of heterophyllin B from Radix Pseudostellaria.

Ultrafine powderRadix PseudostellariaPhysicochemical propertyHPLCHeterophyllin B

冯东燕、孙萍、李萌萌、杨祺、杨雯、刘旭海

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江西中医药大学,南昌 330004

江中药业股份有限公司,南昌 330049

超微粉 太子参 理化性质 高效液相色谱 太子参环肽B

江西省重大科技研发专项

20203ABC28W018

2024

中国处方药
南方医药经济研究所

中国处方药

影响因子:0.649
ISSN:1671-945X
年,卷(期):2024.22(6)
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