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某院中成药处方前置审核结果的回顾性调查研究

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目的 调查某院中成药处方前置审核结果,分析其用药风险问题,为中成药的安全规范应用提供指导。方法 收集 2022 年 4月~2023 年 4 月门急诊药房接收的中成药处方 32 486 份,采用随机抽样方法抽取 16 000 份处方,通过前置审核系统进行审核,对存在问题的中成药处方进行具体分析,对各类问题进行汇总统计分析。结果 16 000 份中成药处方中发现存在相关问题的处方共 684 份,占调查总数的 4。28%。相关问题主要包括重复用药(占比 38。74%)、用法用量不合理(占比 33。04%)等。药物用途主要集中于小儿用药、呼吸道疾病用药、心脑血管疾病用药等方面。部分药物说明书中在成分含量、毒性问题、不良反应、注意事项等方面存在关键信息缺少。结论 在中成药处方的前置审核过程中可发现较多用药风险问题,主要集中于重复用药和用法用量不合理等问题,医药管理系统应完善中成药处方前置审核系统的知识库,加强对毒性药物的警示管理和高频率药物的用药规范管理,以提高中成药的用药安全性和合理性。
Retrospective investigation on the results of pre-review of traditional Chinese patent medicines and simple preparations prescrip-tions in a hospital
Objective To investigate the results of pre-examination of traditional Chinese patent medicines and simple preparations prescriptions in a hospital,analyze the risk of drug use,and provide guidance for the safe and standardized application of traditional Chinese patent medicines and simple preparations.Methods 32 486 prescriptions of traditional Chinese patent medicines and simple preparations received from outpatient and emergency dispensaries from April 2022 to April 2023 were collected,16 000 prescriptions were selected by random sampling,and reviewed by the pre-audit system.The prescriptions of traditional Chinese patent medicines and simple preparations with problems were analyzed concretely,and various problems were summarized and statistically analyzed.Results Among 16 000 traditional Chinese patent medicines and simple preparations prescriptions,684 prescriptions with related problems were found,accounting for 4.28%of the total number of investigations.The related issues mainly include the problem of repeated use of drugs(accounting for 38.74%)and the problem of unreasonable usage and dosage(accounting for 33.04%).The main uses of drugs are concentrated in pediatric medication,respiratory disease medication,cardiovascular and cerebrovascular disease medication,etc.Some drug instructions lack key information in terms of ingredient content,toxicity issues,adverse reactions,and precautions.Conclusion In the process of pre-review of traditional Chinese patent medicines and simple preparations prescriptions,many drug use risks can be found,mainly focusing on repeated drug use and unreasonable usage and dosage.The medical management system should improve the knowledge base of the pre-review system of traditional Chinese patent medicines and simple preparations prescriptions,strengthen the warning management of toxic drugs and the standardized management of high frequency drugs,so as to improve the safety and rationality of traditional Chinese patent medicines and simple preparations use.

Traditional Chinese patent medicines and simple preparations prescriptionPre-auditRetrospective investigationTraditional Chinese patent medicines and simple preparations management

刘琳、刘娜

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北京市密云区中医医院药剂科,北京 101500

中成药处方 前置审核 回顾性调查 中成药管理

2024

中国处方药
南方医药经济研究所

中国处方药

影响因子:0.649
ISSN:1671-945X
年,卷(期):2024.22(6)