Effect of remazolam combined with modified TAPB on postoperative delirium in elderly patients with cervical cancer
Objective To investigate the effect of remazolam combined with modified transversus abdominis plane block(TAPB)on post-operative delirium in elderly patients with cervical cancer.Methods Seventy elderly cervical cancer patients who underwent radical cervical cancer surgery in People's Hospital of Wuwei City from July 2021 to July 2023 were selected and randomly divided into a remazoram group(n=35)and a control group(n=35)using a digital randomization table method.The control group received routine general anesthesia induction,intravenous injection of midazolam+sufentanil+propofol+rocuronium.The remazoram group received intravenous injection of sufentanil+remazoram+rocuronium anesthesia induction.After anesthesia induction,modified TAPB was performed.General vital signs at different time points,awakening indicators,the occurrence of postoperative delirium and adverse reactions were recorded and compared between the two groups.Results Compared with the control group,the incidence of delirium in the remazolam group was lower at 5 days after surgery(P＜0.05),and there was no statistically significant difference between the control group and the remazolam group at 7 days after surgery.,but there was an obvious advantage in the time of eye opening、extubation and stay in the PACU during the recovery period of anesthesia of the remazolam group,and the vital signs were more stable during operation compared to the control group.Conclusion Anesthesia induction with remazolam in elderly patients with cervical cancer surgery has more stable intraoperative vital signs,combined with TAPB,the patient recover faster after surgery,the occurrence of postoperative delirium can be effectively reduced and with high safety.
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