Effect evaluation of rational clinical application of hospital human blood albumin and analysis of pharmaceutical intervention measures
Objective To evaluate the clinical use of human serum albumin before and after the intervention of clinical pharmacists,so as to explore pharmaceutical interventions to promote their rational use.Methods Use of the evidence-based medicine approach,formulate the evaluation standard for rational use of human serum albumin in a hospital,implement pharmaceutical intervention measures to manage the whole process of clinical use of human serum albumin.By using hospital's HIS system,the cases of all hospitalized patients who used human serum albumin in Dong'e County People's Hospital from October 2020 to March 2021(before the intervention)and from October 2021 to March 2022(after the intervention)were selected,to compare the use of human serum albumin before and after the intervention.Results After the intervention,dosages and medication days of human blood albumin were significantly lower than those before the intervention.After the intervention,dosages of indications meeting the evaluation criteria for rational use of human blood albumin were lower than that before the intervention.The proportion of indications meeting the evaluation criteria increased from 81.69%before the intervention to 97.28%after the intervention.The proportion of hypoproteinemia treated before and after intervention decreased from 17.95%to 6.52%.The proportion of rational use of blood albumin before the intervention was 65.57%and 96.74%after the intervention.There were statistical significances in above-mentioned indexes between before and after the intervention(P＜0.05).The proportion had no significant differences on hospital stay,accepted treatment in ICU,organ failure,accepted renal replacement therapy before and after the intervention(P＞0.05).Conclusion The pharmaceutical intervention of clinical pharmacists on human serum albumin in the hospital is feasible and effective.
Clinical pharmacistsHuman serum albuminPharmaceutical interventionRational use of drugs
万方数据
维普
