Analysis of multi-drug resistant bacterial infections in patients with type 2 diabetes
Objective To analyse the multi-drug-resistant bacterial infections in patients with type 2 diabetes mellitus.Methods The clinical data of 326 patients with type 2 diabetes mellitus admitted to a hospital from February 2021 to November 2023 were retrospectively analyzed,and all patients underwent culture of blood,sputum,urine,and secretions to identify and analyze the characteristics of pathogenic bacterial strains and resistance,and to analyze the drug sensitivity of the major gram-negative bacteria,positive bacteria,and fungi.Results 301 strains of pathogenic bacteria were isolated from 326 patients:182 strains of gram-negative bacteria accounted for 60.47%;87 strains of gram-positive bacteria accounted for 28.90%;and 32 strains of fungi accounted for 10.63%.There were 106 cases of multidrug-resistant bacteria,and the number of infected patients over 60 years old accounted for 54.82%of the total number of infected patients;Escherichia coli,Staphylococcus aureus,and Staphylococcus epidermidis were the main pathogens,among which the antimicrobial drugs with high resistance rate of Escherichia coli were ampicillin and furaztoxin,and the resistance rates were 96.12%and 73.64%respectively.Three of the gram-positive bacterias did not show vancomycin-resistont、linezolid-resistant and rifampicin-resistant strains.Conclusion The distribution of pathogenic bacteria in patients with type 2 diabetes mellitus is very wide,and patients are very susceptible to infections,among which the proportion of elderly patients is relatively high,and the resistance of pathogenic bacteria is generally strong,and there exists a high drug resistance and multi-drug resistance,therefore,timely detection of pathogenic bacteria in patients should be carried out,and targeted medication can help to improve the clinical efficacy.
Type 2 diabetesMulti-drug resistant bacteriaInfections
万方数据
维普
