Clinical value of antimicrobial stewardship combined with PDCA management in reducing antibacterial use density in gynecology department of a hospital
Objective To explore the clinical value of antimicrobial stewardship(AMS)combined with Plan-Do-Check-Act(PDCA)management in reducing the antibacterial use density(AUD)in gynecology department of a hospital.Methods A total of 100 patients admitted to the gynecology department of Xuyi County People's Hospital from March 2023 to February 2024 were selected for the research objects.50 patients admitted from March 2023 to June 2023 were selected as the control group and did not receive any antimicrobial management.50 patients admitted from July 2023 to February 2024 were selected as the intervention group and received AMS combined PDCA strategy.The types and proportion of antimicrobial drug use,AUD and irrational drug use were compared between the two groups.Results The primary antimicrobial drug use types in the two groups mainly included cefuroxime,cefazolin,ornidazole and cefoperazone-sulbactam.In the intervention group,the antimicrobial drug use proportions of these four antibiotics[cefuroxime(28.00%),cefazolin(22.00%),ornidazole(20.00%),cefoperazone-sulbactam(40.00%)]were all lower than those in the control group[cefuroxime(72.00%),cefazolin(58.00%),ornidazole(56.00%),cefoperazone-sulbactam(66.00%)],with statistically significant differences(P＜0.05).The AUD in the intervention group was lower than that in the control group.The non-indication medication in the intervention group was lower than that in the control group,and the total irrational medication rate was significantly lower in the intervention group(8.00%)compared to the control group(32.00%)(P＜0.05).Conclusion AMS combined with PDCA management can significantly reduces the proportion of antibacterial drug use,AUD and the incidence of irrational drug use in the hospital,which has significant clinical implications.
AMS combined with PDCAGynecologyAntibacterial use densityClinical value
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