Case analysis and pharmaceutical monitoring of a case of drug induced hypersensitivity syndrome caused by lithium carbonate and zopiclone
Objective To explore the characteristics and key points of pharmaceutical monitoring of drug hypersensitivity reaction caused by the combination of lithium carbonate and zopiclone.Methods Clinical pharmacists participated in the treatment of a patient with drug induced hypersensitivity syndrome,whose primary clinical manifestations were liver function damage and severe skin erythema,after taking lithium carbonate and zopiclone,and adjudged the relationship of two drugs with hypersensitivity reaction according to relative standards,and conduct relevant literature analysis.Results After early identification and discontinuation of the suspected sensitizing drugs and after the treatment of anti-allergy、protecting liver、hormone and improving immunity,the patient's symptoms improved.Conclusion Hypersensitivity reaction is the rare adverse drug reaction of lithium carbonate and zopiclone,when patients experience fever or rash without obvious causes,attention should be paid and medication should be stopped in a timely manner.Clinical pharmacists should assist doctors in conducting relevant literature analysis and evidence-based support.
Lithium carbonateZopicloneDrug induced hypersensitivity syndromePharmaceutical care
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